📍 Istanbul Faculty of Medicine, Çapa 📞 +90 212 414 20 00 senoltonyali@istanbul.edu.tr
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Rezum — Prostate treatment
with water vapor

FDA-approved water vapor therapy. The only BPH treatment that is outpatient, performed under local anesthesia, and preserves sexual function.

Overview

What is done when medication isn't enough?

Rezum is a next-generation, minimally invasive treatment used in benign prostatic hyperplasia (BPH). Sterile water vapor at 103°C is injected into the prostate tissue with an endoscopic needle, causing the enlarged cells to break down naturally.

Rezum stands out as the only BPH treatment that preserves sexual function. Retrograde ejaculation, seen in 75–85% of surgical methods, is below 5% with Rezum. This makes it unique for men with an active sex life.

It received FDA approval in 2015 and European CE approval in 2016, and is performed at a limited number of centers in Turkey.

Who is Rezum suitable for?

  • Those who experience side effects from medications or an inadequate response
  • Men with an active sex life who do not want to lose ejaculation
  • Those with a prostate size between 30–80 grams
  • High anesthesia-risk patients who cannot receive general anesthesia
  • Those who want to return to work in 2–3 days
  • Men who plan to have children
Anatomy

How is Rezum performed?

Water vapor (103°C) is injected into the prostate tissue from a device in the urethra. The vapor spreads through the tissue and causes cell death; the enlarged prostate shrinks over time.

Rezum — water vapor injection into the prostate
Rezum — water vapor therapy
Process

The procedure step by step

The Rezum procedure is done as an outpatient, in an office or hospital setting. The patient goes home the same day.

i. Assessment

Patient Consultation

Prostate size and structure are assessed with PSA, uroflowmetry and ultrasound. Suitability for Rezum is determined.

ii. Preparation

Local Anesthesia

Local anesthesia or mild sedation is applied. No general anesthesia is needed. The patient undergoes the procedure awake and pain-free.

iii. Procedure

Vapor Injection

The endoscope is advanced through the urethra to prostate level. 4–10 vapor injections, each lasting 9 seconds, are performed. The whole procedure takes 5–10 minutes.

iv. Follow-up

Going Home

Discharge with a catheter. The catheter is removed in 3–5 days. The effect begins in weeks 2–4, with the maximum result at month 3.

Process

Vapor injection points

Water vapor is delivered to the enlarged prostate from multiple points in both lobes. Each injection targets a specific portion of the tissue.

Rezum vapor injection points
Rezum — injection points distributed across the prostate
Advantages

The advantages of Rezum

The quality-of-life advantages Rezum offers compared with surgical treatments.

i.

Sexual function preserved

Normal ejaculation is preserved in 95% of patients. In HoLEP and TUR-P this rate is 15–25%.

ii.

Outpatient treatment

There is no hospital stay. 1–2 hours of observation after the procedure, then home.

iii.

Local anesthesia

No general anesthesia risk. A safe option for cardiac and pulmonary patients and older individuals.

iv.

Quick return

Return to work in 2–3 days. HoLEP and TUR-P require at least a week.

v.

Stopping medication

The vast majority of patients can stop their BPH medications completely after treatment.

vi.

5 yr+ efficacy

In 5-year follow-up studies, 95% of patients are satisfied with the treatment. Recurrence rate is 4–5%.

How It Works

How does the vapor affect the tissue?

The water vapor from the needle spreads through the prostate tissue, creating controlled cell death; over time the tissue shrinks and the pressure on the urethra decreases.

Effect of Rezum vapor on prostate tissue
The vapor spreads through the tissue and shrinks it
Frequently Asked Questions

What patients ask most

Evidence-based answers to common questions about Rezum treatment.

Is Rezum treatment painful?

It is done under local anesthesia and no pain is felt. There may be mild burning and urgency for 1–2 weeks after the procedure; this is easily managed with simple painkillers.

When will I see results?

Rezum is a "slow-acting" treatment. The effect begins in 2–4 weeks and the maximum result is achieved at month 3. This period depends on the body absorbing the treated tissue.

How is my sex life affected?

Rezum fully preserves sexual function. Normal ejaculation continues in 95% of patients. No deterioration in erectile function is seen; some patients even report improved sexual performance as the side effects of BPH medications disappear.

Up to what prostate size is it suitable?

It gives the best results for prostates between 30–80 grams. Above 80 grams, HoLEP is a better option.

Can I stop my medications?

At the 3-month check, medications are gradually reduced with your doctor's assessment. The vast majority of patients can stop BPH medications completely after Rezum.

Appointment

Is Rezum right for you?

Bring your PSA, uroflowmetry and ultrasound results. Based on your prostate volume, let's assess together whether Rezum is the right treatment.