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Prostate Cancer

One of the most common cancers in men — but when caught early, the treatment success rate is very high. The key: regular check-ups.

Overview

What is prostate cancer?

Prostate cancer occurs when cells in the prostate gland multiply uncontrollably. Cancer most often starts in the outer part of the prostate (the peripheral zone) — this is different from the inner region where benign enlargement (BPH) develops.

An important feature of prostate cancer is that it often progresses slowly. In many patients the cancer stays silent for years and does not threaten life. However, some types can be aggressive. The aim, therefore, is to catch the aggressive kind early while protecting slow-growing ones from unnecessary treatment.

In the early stage, prostate cancer causes almost no symptoms. That is why early diagnosis relies on regular PSA checks and examination done without waiting for complaints. In prostate cancer caught early, the treatment success rate is very high.

Risk factors

  • Age: Risk rises markedly after age 50
  • Family history: Prostate cancer in a father or brother increases risk
  • Genetics: Certain inherited gene changes (e.g. BRCA) carry risk
  • Ethnicity: Risk is higher in some populations
  • Diet: A diet heavy in animal fat has been linked to it
Anatomy

The zones of the prostate and cancer

Prostate cancer most often begins in the peripheral zone, which makes up the outer part of the prostate. Benign enlargement (BPH), on the other hand, develops in the transition zone around the urethra — this is why the two are separate diseases.

Zonal anatomy of the prostate — peripheral, central, transition zones and anterior fibromuscular stroma
Prostate zones — about 70% of cancers begin in the peripheral zone
Symptoms

When does it cause symptoms?

Early prostate cancer is silent. The symptoms below usually appear in advanced disease — which is why screening without waiting for symptoms is important.

i.

Voiding changes

Weak flow, frequent urination, straining. However, these symptoms mostly belong to benign enlargement (BPH).

ii.

Blood in urine or semen

Blood seen in the urine or semen is a finding that needs to be investigated.

iii.

Bone pain

Persistent pain in the lower back, hip or back can point to bone involvement in advanced disease.

iv.

Erectile problems

New-onset erectile dysfunction may rarely accompany it; it can also have other causes.

v.

Unintended weight loss

Unexplained weight loss and weakness are general symptoms that can be seen in advanced disease.

vi.

Usually: no symptoms

The most important message: early cancer causes no symptoms. That is why regular PSA checks save lives.

Diagnosis

How is it diagnosed?

Diagnosing prostate cancer proceeds step by step. The aim is to avoid unnecessary procedures while not missing significant cancer.

i. Screening

PSA & Examination

A blood PSA measurement and a digital rectal exam form the basis of the first assessment.

ii. Imaging

Multiparametric MRI

In suspicious cases, prostate MRI shows risky regions and reduces unnecessary biopsies.

iii. Biopsy

Definitive Diagnosis

When needed, an MRI-guided targeted prostate biopsy provides a definitive diagnosis and determines the grade of the cancer.

iv. Staging

Spread Assessment

In necessary cases, additional imaging assesses whether the cancer has spread; treatment is planned accordingly.

Treatment

Treatment options

In prostate cancer, treatment is personalized according to the grade and stage of the cancer, age and general health. The "best treatment" can be different for each patient.

Active surveillance

In low-risk, slow-growing cancers; close follow-up instead of deferring treatment. It protects from unnecessary side effects.

Radical prostatectomy

Complete surgical removal of the prostate. Nerve-sparing techniques aim to preserve function.

Radiotherapy

Destroying cancer cells with radiation therapy. In some patients it can be an alternative to surgery.

Hormone & advanced therapies

In advanced disease, hormone therapy and current systemic treatments keep the disease under control.

Frequently Asked Questions

What patients ask most

The most common questions about PSA, screening age and treatment decisions.

Does a high PSA mean cancer?

No. A high PSA can also be due to benign enlargement, infection (prostatitis) or recent sexual activity. A high PSA only shows that further assessment is needed; on its own it does not diagnose cancer.

At what age should I start screening?

In general, PSA checks are recommended from age 50. If there is a family history of prostate cancer or you are in a high-risk group, this age can be brought down to 45. We determine the most appropriate screening plan together.

Does prostate cancer always require surgery?

No. In low-risk, slow-growing cancers, "active surveillance" can be preferred — that is, close follow-up instead of immediate treatment. The treatment decision is personalized according to the grade and stage of the cancer, your age and your preferences.

Will treatment affect my sexual and urinary function?

Depending on the type of treatment, erectile function and urinary control can be affected. Modern nerve-sparing surgery and advanced radiotherapy techniques reduce these risks. Possible effects are discussed openly before treatment.

What is the chance of recovery if caught early?

In early-stage cancers confined to the prostate, the treatment success rate is very high and long-term survival rates are quite good. This is why regular check-ups done without waiting for symptoms are of great importance.

Appointment

Regular check-ups save lives

In prostate cancer, early diagnosis changes everything. Put your mind at ease with a simple PSA test and examination. You can reach out via WhatsApp for assessment and a preliminary consultation.